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Immunocytochemistry
F ig . 3 5 .1 1 Fine-needle aspira tio n c y to lo g y o f a re n a l c e ll c a rc in o m a . (A) Cell b lo ck is m o d e ra te ly ce llu la r w ith tu m o r cells sh o w in g a b u n d a n t va cuo la te d
cyto p la sm . (B) C D 1 0 and (C) v im e n tin stro n g ly d iffu se ly p ositive in tu m o r cells.
A
C
F ig . 3 5 .1 2 A 76-year-old m an w ith a re tro p e rito n e a l mass: u ltra s o u n d -g u id e d fin e -n e e d le aspira tio n c y to lo g y o f th e mass is p erfo rm e d . (A and B) Aspirates are
a b u n d a n tly cellular. (C and D) Cell b lo ck show s a b u n d a n tly cellular, dyscohesive clusters o f u n ifo rm a typ ica l e p ith e lio id cells in a va g u e ly m icroa cina r pattern.
(E) C y to k e r a tin - 7 and (F) c y to k e r a tin - 2 0 are stro n g ly p ositive in tu m o r cells. (G and H) S trong p o sitivity o f th e tu m o r cells fo r n e u ro e n d o crin e m arkers
s y n a p to p h y s in and C D 5 6 . (I) V im e n tin is also p ositive in tu m o r cells. Based o n th e c y to m o rp h o lo g y and im m u n o sta in , th e tu m o r w as c o n firm e d to be
m e ta s ta tic c a rc in o id arising fro m d u o d e n u m .
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