7
Microbiology, inflammation, and Viral infections
Fig. 7.76 Detached ciliary tuft (DCT).
Vaginopancervical smear
(Papanicolaou x OI).
recently been reported.129 HPV-associated lesions occur more
commonly among HIV-positive women. There appears to be
correlation between the high-grade
cervical
intraepithelial
changes and lower CD4 values.
Concluding Remarks
In this chapter we document the cytomorphologic features and
identification of the various female genital tract infections. Gen-
ital tract infections are far more common than the neoplasm,
and cause considerable morbidity and economic loss. Personal
hygiene, sexual habits, self-medication, and contraceptive prac-
tices contribute to the occurrence of many of these diseases
and associated cellular changes. While an accurate diagnosis of
these infections (
Candida
) can reduce complications and mor-
bidity, familiarity and recognition of cytomorphologic features
(IUD, herpes) is critical in proper interpretation and diagnosis
of many epithelial neoplastic processes. International Academy
of Cytology recommended the identification of many of these
infections as "an integral part of the general diagnostic workup
and of good patient care."130
Some uncommon neoplastic lesions (Langerhans histiocyto-
sis-X, pemphigus) have been included; they have morphologic
features that mimic infectious and neoplastic processes and an
awareness and accurate diagnosis is critical. A number of uncom-
mon infections are included not only for a comprehensive cov-
erage but to emphasis the changing environment and emerging
geographic cytopathology.
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