Benign Proliferative Reactions, Intraepithelial Neoplasia, and Invasive cancer of the Uterine cervix
Fig. 8.96 Villoglandular (papillary) adenocarcinoma in situ/adenocarcinoma. (A) Papillary growth pattern, with severe pseudostratification visible
in the upper right-hand corner (H&E x MP). (B) Papillary structure composed of severely atypical glandular cells (Papanicolaou x MP).
Fig. 8.97 Carcinoma in situ (HGSIL) and adenocarcinoma in situ/adenocarcinoma in liquid-based cytology specimen (LBCS). (A) Red arrow:
highly abnormal squamous cells with scanty cytoplasm and polymorphic nuclei corresponding with carcinoma in situ. Blue arrow: strip-like arrangement
composed of glandular cells exhibiting elongated nuclei, varying in size (LBCS, Pap x LP). (B) Glandular cells showing elongated nuclei, varying in size. The
chromatin is coarsely granular and irregularly distributed. Feathering is demonstrated (LBCS, Papanicolaou x HP). (C) Highly atypical squamous cells exhibiting
polymorphism, hyperchromasia, and a coarse chromatin pattern (LBCS, Papanicolaou x HP).