PART TWO
Diagnostic Cytology
If the cytologic result is malignant, surgery (total thyroidec-
tomy) is the recommended procedure. Patients with indetermi-
nate or suspicious smears can be reaspirated or directly operated
on with intraoperative consultation. If the cytologic results are
benign, no further immediate diagnostic studies are required;
however, cytologically benign but clinically suspicious lesions
should be excised. Surgery is also indicated in benign lesions
with neck disfigurements and local symptoms. Patients with
unsatisfactory smears should be reaspirated.
Although immunohistochemistry and cytometry do not help
in differentiating benign from malignant nodules in specific
cases with indeterminate lesions molecular biology techniques
have promising perspectives.
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